ABC transporters in antibiotic-producing actinomycetes
نویسندگان
چکیده
منابع مشابه
Interlocking of primary and secondary metabolism in antibiotic-producing actinomycetes
Glycopeptides such as vancomycin are the drugs of last resort for the treatment of severe infections caused by antibiotic resistant gram-positive bacteria. As a model strain for analysing and manipulating glycopeptide biosynthesis we have chosen Amycolatopsis balhimycina which synthesizes the vancomycin-type glycopeptide balhimycin. The 66-kb gene cluster encoding the biosynthesis of balhimycin...
متن کاملRules for the classification of antibiotic-producing actinomycetes.
One of the most important tasks in our present day science of antibiotics is the establishment of a completely rational taxonomy and nomenclature for antibiotic-producing organisms. A purposeful search for antibiotic substances is possible only with good knowledge of the species which produce them. A great many antibiotic-producing actinomycetes have been described recently. Investigators often...
متن کاملIdentification and Characterization of Antibiotic-producing Actinomycetes Isolates
Actinomycetes are a gram-positive, filamentous subgroup of bacteria most known for antibiotic production. In fact, most of the antibiotics available today have originated from actinomycetes, namely from the genus Streptomyces. Novel bacteria with antimicrobial activities have been discovered from bacterial screen studies for decades and there is still much more yet to be unearthed. One hundred ...
متن کاملAbc Transporters in Mitochondria
Mitochondria are essential organelles of most eukaryotic cells including fungi, invertebrates, vertebrates and plants. They perform various processes such as oxidative phosphorylation, the tricarboxylic acid cycle, fatty acid oxidation, the biosynthesis of various amino acids, the generation of iron-sulfur (Fe/S) clusters and their insertion into apoproteins, as well as partial reactions of hem...
متن کاملStructure of ABC transporters.
ABC (ATP-binding cassette) transporters are primary active membrane proteins that translocate solutes (allocrites) across lipid bilayers. The prototypical ABC transporter consists of four domains: two cytoplasmic NBDs (nucleotide-binding domains) and two TMDs (transmembrane domains). The NBDs, whose primary sequence is highly conserved throughout the superfamily, bind and hydrolyse ATP to power...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1998
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.1998.tb12792.x